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One transcript contains exon 3 and 4, the second contains exons 1, 3 and 4 and the third contains all four exons.

No pathogenic mutation was detected in the exon and franking regions of MYH9 gene except a synonymous mutation(A1143A) in the exon 25.

Objectives To study the feature of disease causing mutation of exon 12 of Wilson disease (WD) gene in Chinese and evaluate its value in direct gene diagnosis.

The mutations, including in-frame deletions at exon 19 and substitutions at exon 18 or exon 21, cluster around ATP-binding pocket of TK domain.

Objective To analyze the mutation characterization in exon 8 of ATP7B gene in Chinese Patients with Wilson disease(WD).

exon造句

Results the DHPLC find the exon 7, 9 polymorphism.

Objective To explore the mutation of RET gene exon 11 in sporadic medullary thyroid carcinoma and to clarify the relationship between RET mutation and sporadic medullary thyroid carcinomas.

Methods Polymerase chain reaction(PCR)was used for 12 JAK2V617F -negative PV patients to amply the region of JAK2 exon 12, direct gene sequencing was performed to detect mutations of JAK2 exon 12.

ConclusionThe prevalence of the mutation genotype and the mutation allele of PAFAH exon 9 in patients with ACI is significantly increased.

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